Repositorio Institucional Fleni

El Repositorio Institucional Fleni tiene el objetivo reunir, almacenar, preservar y difundir la producción científico-académica de la Institución producto de sus actividades de investigación y docencia, a fin de ponerlas a disposición de la comunidad para su uso, tendiendo a aumentar la visibilidad y la difusión de los documentos generados y colaborar así en la construcción de su memoria institucional.

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  • Integrating city design into lifestyle trials: urban greenness shapes physical activity levels across 12 cities in the LatAm FINGERS trial. 
    Spiousas, Ignacio; Coldeira, María Florencia; Suemoto, Claudia Kimie; Baena, Ana Y.; Salinas‐Contreras, Rosa Maria; Caramelli, Paulo; Brucki, Sonia; Nitrini, Ricardo; Sosa, Ana Luisa; Crivelli, Lucía; Sevlever, Gustavo; Custodio, Nilton; Acosta, Daisy M.; Charamelo, Ana; Salas, Jorge Leon; Delgado, Carolina; Cusicanqui, María Isabel; Jimenez Velazquez, Ivonne Z.; Duque, Lissette; Calandri, Ismael Luis (Alzheimer´s Association, 2025-12-23)
    Background: LatAm FINGERS is a feasibility trial aimed at preventing cognitive decline in individuals at risk through lifestyle changes in Latin America, with its objectives aligned with the RE‐AIM (Reach, Effectiveness, ...
  • Can Yerba Mate Reduce the Risk of Cognitive Impairment? A pilot study 
    Gilbert, Afra; Gatto, Emilia; Chocobar, Nicolas; Seguí, Josefina; Crotti, Beatriz; Cubas Guillen, Jonathan; Merchan del Hierro, Xavier; Bacigalupe, Lucia; Persi Gabriel, Gustavo; Melcon, Carlos Mario; O'Neill, Santiago; Múnera Martínez, Claudia Patricia; Sierra Sanjurjo, Natalia; Rojas, Galeno; Tribbia Liliana, Teresita; Taravini, Irene (Alzheimer´s Association, 2025-12-23)
    Background: Yerba mate (YM), an infusion made from Ilex paraguariensis, is widely consumed in Argentina and other South American countries. Experimental studies have shown that YM enhances antioxidant defenses, increases ...
  • Baseline Results Investigate APOE‐Memory Connection in Latin‐American Population at Risk for Dementia ‐ LatAm‐FINGERS Initial Insights 
    Vasconcelos Friedlaender, Clarisse; Cruz de Souza, Leonardo; Tonidandel Barbosa, Maira; Braga Gomes, Karina; Tosatti, Jéssica Abdo Gonçalves; Rocha, João Victor de Faria; Melillo Cardoso, Davi; Machado Prates, Marcelo; Lopes, Andre Luis; Silva Vieira, Vitoria; Ribeiro Jeunon, Vinicius; Ferreira de Souza, Letícia Maria; Soares Figueiredo, Lais; Andrades, Andreia; Crivelli, Lucía; Calandri, Ismael Luis; Martin, Maria Eugenia; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio (Alzheimer´s Association, 2025-12-21)
    Background: Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued ...
  • Ageism in a Latin American Cohort: The Role of Cognition and Gender 
    Arruabarrena, Micaela Maria; Corvalan, Nicolás; Morello Garcia, Florentina; Keller, Greta; Martinez, Carlos; Crivelli, Lucía (Alzheimer´s Association, 2025-12-26)
    Background: Ageism, a form of discrimination based on age‐related stereotypes, encompasses both negative (e.g., older adults as burdensome or incapable) and positive (e.g., older adults as wise or nurturing) stereotypes. ...
  • Use of an exogenous DNA-free system to generate MSTN-KO calves by CRISPR/Cas9 and SCNT 
    Suvá, Mariana; Bastón, Juan Ignacio; Wiedenmann, Elisabet Astrid; Pose Ortiz de Rozas, María Belén; Roberto, Jordán; Ghetti, Alberto; Viale, Diego Luis; Moro, Lucia Natalia; Vichera, Gabriel Damián (Elsevier, 2025-09-25)
    This study aimed to obtain myostatin (MSTN)-knockout calves, while avoiding the risk of exogenous DNA integration during gene editing. To achieve this, we combined CRISPR/Cas9 ribonucleoprotein gene editing with somatic ...

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